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    World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) Guideline:
    anthelmintic combination products targeting nematode infections of ruminants and horses (2012)

    Art
    Zeitschriftenartikel / wissenschaftlicher Beitrag
    Autoren
    Geary, T. G.
    Hosking, B. C.
    Skuce, P. J.
    von Samson-Himmelstjerna, G (WE 13)
    Maeder, S.
    Holdsworth, P
    Pomroy, W
    Vercruysse, J.
    Quelle
    Veterinary Parasitology; 190(1/2) — S. 306–316
    ISSN: 0304-4017
    Sprache
    Englisch
    Verweise
    DOI: 10.1016/j.vetpar.2012.09.004
    Kontakt
    Institut für Parasitologie und Tropenveterinärmedizin

    Robert-von-Ostertag-Str. 7-13
    Gebäude 35, 22, 23
    14163 Berlin
    +49 30 838 62310
    parasitologie@vetmed.fu-berlin.de

    Abstract / Zusammenfassung

    Increasing threats from anthelmintic resistant nematode populations warrant and motivate a reappraisal of chemotherapeutic strategies for nematode control in ruminant livestock and horses. The objective of this paper is to present a guideline for the evaluation of products containing two or more constituent anthelmintic actives in a single dosage form for the treatment of nematode infections in these animals. At present, regulatory policies on the approval of such products vary across jurisdictions, and this World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) guideline should enable the harmonization of the requirements. This guideline makes clear recommendations on the minimal standards needed, but stresses that registration dossiers for combination anthelmintic products submitted for approval must conform to the standards and practices already established in existing guidelines for anthelmintics.