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    Quantitation of angiogenesis and antiangiogenesis in vivo, ex vivo and in vitro - an overview (2009)

    Art
    Zeitschriftenartikel / wissenschaftlicher Beitrag
    Autoren
    Bahramsoltani, Mahtab
    Plendl, Johanna (WE 1)
    Janczyk, Pawel
    Custodis, Pia
    Kaessmeyer, Sabine (WE 1)
    Quelle
    Alternativen zu Tierexperimenten / Alternatives to animal experimentation; 26(2) — S. 95–107
    ISSN: 1868-596x
    Sprache
    Englisch
    Verweise
    Pubmed: 19565167
    Kontakt
    Institut für Veterinär-Anatomie

    Koserstr. 20
    14195 Berlin
    Tel.+49 30 838 53555 Fax.+49 30 838-53480
    email:anatomie@vetmed.fu-berlin.de

    Abstract / Zusammenfassung

    Angiogenesis is defined as the sprouting of new capillaries from pre-existing ones. Angiogenesis is a prerequisite for growth and differentiation of organs and tissues and is involved in many pathological processes, for example growth and metastasis of tumours. Numerous in vivo and in vitro models of angiogenesis have been developed in order to identify and analyse pro- and antiangiogenic factors. This review aims at outlining the topic of quantitation of angiogenesis and antiangiogenesis in these models.