Publikationsdatenbank

Quantitation of angiogenesis and antiangiogenesis in vivo, ex vivo and in vitro - an overview (2009)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Bahramsoltani, Mahtab

Plendl, Johanna (WE 1)

Janczyk, Pawel

Custodis, Pia

Kaessmeyer, Sabine (WE 1)

Quelle

Alternativen zu Tierexperimenten / Alternatives to animal experimentation

Bandzählung: 26

Heftzählung: 2

Seiten: 95 – 107

ISSN: 1868-596x

Sprache

Englisch

Verweise

Pubmed: 19565167

Kontakt

Institut für Veterinär-Anatomie

Koserstr. 20
14195 Berlin
+49 30 838 53555
anatomie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Angiogenesis is defined as the sprouting of new capillaries from pre-existing ones. Angiogenesis is a prerequisite for growth and differentiation of organs and tissues and is involved in many pathological processes, for example growth and metastasis of tumours. Numerous in vivo and in vitro models of angiogenesis have been developed in order to identify and analyse pro- and antiangiogenic factors. This review aims at outlining the topic of quantitation of angiogenesis and antiangiogenesis in these models.