Königsweg 65
14163 Berlin
+49 30 838 62261
klauentierklinik@vetmed.fu-berlin.de
High milk performance connected with sound health regarding metabolism and sufficient fertility in dairy cows depends on a well bal-
anced distribution of energy in the body.The concentration of glucose in the blood is relatively constant. Enzymes, hormones, controlling proteins and transporters contribute to the enormous synthesis production
of 3 to 4 kg glucose.These are capable of in fluencing the efficiency of
glucose production and distribution.Glucose and growth hormone as
“early predictors ”are superior to other possible parameters such as free
fat acids,urea,thyroxin,prolactin,somatropin and IGF-1 in compar-
ing the relationship between physiological metabolic parameters and the
performance of cows and sires.Insulin plays an outstanding role based
on its central position in energy metabolism.The function of insulin may
be recorded by means of the intravenous glucose tolerance test (GTT).
The reaction of insulin and glucose was investigated after infusion of
1 g glucose per kg 0 .75 because of the probable genetic determination
of the reactive ability.The coe .cient of heritability was estimated as
h 2 =0.28 ±0.16.The metabolic reaction for young cattle was the same
for females and males as the GTT-parameters basic concentration of
glucose was 4.0,4.2 and 4.1 nmol/l plasma and the glucose half-life was
51.0,49.2 and 50.3 minutes for heifers (n=22)and young sires (n=20,
n=87),respectively.The di .erences of insulin and glucose show a con-
trary course and depend on the age under standardized feeding.The
correlation between GTT and o .spring breeding value (EBV)is also in-
.uenced by the age (in half-life years).The best correlation is read at
the 3rd half-year.Three independent groups of 24 and 28 young sires
and 12 heifers were involved in the investigation.The correlation coe .-
cients between the glucose half-life (GHWZ)and the o .spring breeding
value (EBV)of about -0.4 to -0.5 are higher compared to the pedigree
breeding value (PBV).If the so far achieved results are con .rmed,an
additional recommendation for the evaluation of breeding bulls before
the start of the progeny test could be given.The test capacity could be
extended or costs for testing bulls could be lowered