Publikationsdatenbank

Feline T-Cell Receptor gamma V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats (2010)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Weiss, Alexander Thomas Andreas

Hecht, Werner

Reinacher, Manfred

Quelle

Veterinary medicine international

Bandzählung: 2010

Seiten: 7

ISSN: 2042-0048

Sprache

Englisch

Verweise

URL (Volltext): http://www.hindawi.com/journals/vmi/2010/953272/

DOI: 10.4061/2010/953272

Pubmed: 20634910

Kontakt

Institut für Tierpathologie

Robert-von-Ostertag-Str. 15
14163 Berlin
+49 30 838 62450
pathologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

The variable domains of antigen receptors are very diverse and assembled in a modular system from a number of V-, D-, and J-region genes. Here we describe additional variants of V- and J-region genes of the feline T-cell receptor gamma (TRG) as well as the corresponding RSSs retrieved from Trace Archive of feline genomic sequences. Additionally, an unusually recombined TRGV-domain containing a partial inverted repeat of the included J-region and a short interspersed element of the CAN-SINE family located within the feline T-cell receptor gamma locus are also described.