Publikationsdatenbank

Die Bedeutung der Infektion mit dem equinen Herpesvirus Typ 1 (EHV-1) in einem deutschen Vollblutgestüt:
Impfung, Abortgeschehen und Diagnostik (2000)

Art

Zeitschriftenartikel / wissenschaftlicher Beitrag

Autoren

Schroer, U

Ludwig, H.

Borchers, K.

Lange, A

Glatzel, Peter

Quelle

Berliner und Münchener tierärztliche Wochenschrift : BMTW

Bandzählung: 113

Seiten: 53 – 59

ISSN: 1439-0299

Kontakt

Tierklinik für Fortpflanzung

Königsweg 65
Haus 27
14163 Berlin
+49 30 838 62618
fortpflanzungsklinik@vetmed.fu-berlin.de

Abstract / Zusammenfassung

The aim of the present study was to clarify whether an EHV-1 induced abortion can be prognosticated by an increase of antibody titres, virus shedding and/or viraemia and whether the current abortion diagnostic is suitable. In this context the immune response post immunization and a possible reactivation were of great interest. For this purpose blood samples of 32 mares between the ages of 5-21 years were regularly investigated during a period of two years before and after vaccination and pregnancy. Neutralization tests, indirect immunofluorescence tests as well as PCR and virus isolation were used for EHV-1 diagnostics. It could be shown that the horses reacted individually to vaccination. In 14 cases a EHV-1-reactivation was suggested. An abortion prognosis was not possible even using serological, virological and molecular biological parameters. In addition, virus shedding and antibody titres were individual. An acute infection was detectable by a significant rise of antibodies and viraemia as well as virus shedding in the secretions. For the abortion diagnostics the antigen detection in combination with virus isolation and PCR from fetal lungs gave reliable results. In addition, the virological and serological investigation of the mare is recommendable. For prophylaxis we would advise a regular vaccination and strict hygiene.