Publikationsdatenbank

Magnesium homeostasis in ruminants and grass tetany (2001)

Art

Buchbeitrag

Autoren

Martens, H.

Schweigel, M.

Quelle

Advances in magnesium research : nutrition and health — Rayssiguier Y (Hrsg.)

Eastleigh; UK: Libbey, 2001 — S. 475–481

ISBN: 0-86196-609-0

Kontakt

Institut für Veterinär-Physiologie

Oertzenweg 19 b
14163 Berlin
+49 30 838 62600
physiologie@vetmed.fu-berlin.de

Abstract / Zusammenfassung

Homeostasis of Mg metabolism depends on the sufficient Mg inflow from the gut into the extracellular fluid (ECF), which must exceed outflow because a hormonal mobilization of Mg from bones is not possible. The surplus of Mg (positive imbalance=inflow > outflow) is excreted via urine maintaining normal plasma Mg concentration. Hypomagnesaemia and grass tetany is a "classical" metabolic disorder of Mg homeostasis. The pathogenesis of this disease is characterized by a reduced inflow of Mg into the ECF and an increased outflow from the ECF, mainly into milk. This negative imbalance -- outflow > inflow -- is a consequence of a variety of factors which can be considered as "man made". Studies of the last decades have significantly improved our knowledge in assessing these factors and hence permit recommendations for a successful prophylaxis