Fachbereich Veterinärmedizin



    Magnesium homeostasis in ruminants and grass tetany (2001)

    Martens, H.
    Schweigel, M.
    Advances in magnesium research : nutrition and health — Rayssiguier Y (Hrsg.)
    Eastleigh; UK: Libbey, 2001 — S. 475–481
    ISBN: 0-86196-609-0
    Institut für Veterinär-Physiologie

    Oertzenweg 19 b
    14163 Berlin
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    Abstract / Zusammenfassung

    Homeostasis of Mg metabolism depends on the sufficient Mg inflow from the gut into the extracellular fluid (ECF), which must exceed outflow because a hormonal mobilization of Mg from bones is not possible. The surplus of Mg (positive imbalance=inflow > outflow) is excreted via urine maintaining normal plasma Mg concentration. Hypomagnesaemia and grass tetany is a "classical" metabolic disorder of Mg homeostasis. The pathogenesis of this disease is characterized by a reduced inflow of Mg into the ECF and an increased outflow from the ECF, mainly into milk. This negative imbalance -- outflow > inflow -- is a consequence of a variety of factors which can be considered as "man made". Studies of the last decades have significantly improved our knowledge in assessing these factors and hence permit recommendations for a successful prophylaxis