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    Zur Rolle des caninen Herpesvirus Typ 1 (CHV-1) bei der Keratitis superficialis chronica (KSC) im Zusammenhang mit einer Strontium 90 Strahlentherapie (2001)

    Art
    Zeitschriftenartikel / wissenschaftlicher Beitrag
    Autoren
    Grüning, G.
    Wolfinger, U.
    Hocht, S.
    Hinkelbein, W.
    Rudolph, R.
    Brunnberg, L.
    Quelle
    Kleintier-Praxis; 46 — S. 699–705
    ISSN: 0023-2076
    Kontakt
    Klinik für kleine Haustiere

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    Haus 1
    14163 Berlin
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    email: kleintierklinik@vetmed.fu-berlin.de

    Abstract / Zusammenfassung

    The exact aetiology of chronic superficial keratitis (CSK) still remains unknown. In this study, 8 corneal and 13 conjunctival biopsies of affected eyes were examined by means of a PCR for herpes DNA. This was done since canine herpesvirus CHV-1 might play a role in the immune-mediated pathogenesis of this disease. A single conjunctival biopsy taken 7 days after radiation therapy with Strontium 90 was positive for CHV-1. In human opthalmology, a reactivation of herpes infection after laser therapy is well described. This may also be the reason for the positive PCR obtained in teh study.