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    Identification and Characterization of Inhibitory Factors of Probiotic Escherichia (E.coli) Strain Nissle 1917 for the Prevention of Invections caused by Shiga Toxin producing E.coli

    Projektbeschreibung:

    Diarrhea is a common problem in children worldwide and in particular in the socioeconomically developing world where more than one billion diarrhea episodes with an estimated 2 to 2.5 million deaths occur every year (O’Ryan et al. 2005). One of the significant causes of diarrhea is the group of Diarrheagenic E. coli. Among these Enterohemorrhagic Escherichia coli (EHEC) have recently been recognized as an emerging food-borne pathogen (Kaper et al. 2004). Here the molecular effects of the interaction between the probiotic Nissle and various EHEC strains is analysed.

    Projektleitung: Univ.-Prof. Dr. Lothar H. Wieler
    Eintragende Einrichtung: Institut für Mikrobiologie und Tierseuchen
    Projektlaufzeit: 01.12.2010 bis 30.11.2012
    Projekttyp: Forschungsprojekt
    Mittelgeber: Alexander von Humboldt Stiftung